梁燕，博士，海燕策略线路1book特聘教授。1989年7月出生，2016年于四川大学硕博连读获高分子化学与物理博士学位，同年以青年卓越人才身份加入海燕策略线路1book工作。 

主要致力于智能响应型缓控释载体材料及各类新型生物降解高分子载体材料的研发，迄今为止，以第一作者或通讯作者在NPG Asia Materials, Biomaterials, ACS Applied Materials & Interfaces, Nanoscale, Journal of Nanobiotechnology, Organic & Biomolecular Chemistry等国际知名期刊发表SCI论文二十余篇；主持国家自然科学基金、山东省自然科学基金、中国博士后科学基金面上资助、青岛市博士后应用研究、海燕策略线路1book卓越人才启动经费各1项；参与国家自然科学基金、欧盟合作项目等六项。任ACS Nano、ACS Applied Materials & Interfaces等杂志审稿人。

目前主要研究方向：

1.多功能药物载体材料与系统的构建；

2.仿生药物载体材料的构建与研究；

3.生物降解高分子组织工程支架材料。

代表性成果：

1. Xuehua Long, Jianqin Yan, Zhuoran Zhang, Jing Chang, Bin He, Yong Sun*, Yan Liang*. Autophagy-targeted nanoparticles for effective cancer treatment: advances and outlook. NPG Asia Materials. 2022, 14, 71.

2. Jianqin Yan, Chan Shan, Caili Liang, Jinting Han, Bin He*, Yong Sun, Kui Luo, Jing Chang, Xianwen Wang, Yan Liang*. Smart Multistage “Trojan Horse”-Inspired Bovine Serum Albumin-Coated Liposomes for Enhancing Tumor Penetration and Antitumor Efficacy. Biomarcomolecules. 2022, 23, 5202-5212. (Front Cover)

3. Mengdi Wang, Zhuoran Zhang, Qingqing Huo, Maolong Wang, Yong Sun*, Hongling Liu, Jing Chang, Bin He, Yan Liang*. Targeted polymeric nanoparticles based on mangiferin for enhanced protection of pancreatic β-cell and type 1 diabetes mellitus efficacy. ACS Applied Materials & Interfaces. 2022. 14: 11092-11103.

4. Jianqin Yan, Xiaohui Zhan, Zhuangzhuang Zhang, Keqi Chen, Maolong Wang, Yong Sun*, Bin He, Yan Liang*. Tetrahedral DNA nanostructures for effective treatment of cancer: advances and prospects. Journal of Nanobiotechnology. 2021. 19: 412.

5. Jianqin Yan, Zhuangzhuang Zhang, Xiaohui Zhan, Keqi Chen, Yuji Pu, Yan Liang*, Bin He. In situ injection of dual-delivery PEG based MMP-2 sensitive hydrogels for enhanced tumor penetration and chemo-immune combination therapy. Nanoscale. 2021. 13, 9577-9589. (Front Cover)

6. Wenxia Gao,Yan Liang*, Xinyu Peng, Yalong Hu, Longgui Zhang, Huayue Wu, Bin He*. In situ injection of phenylboronic acid based low molecular weight gels for efficient chemotherapy. Biomaterials, 2016, 105: 1-11.

7. Yan Liang, Wenxia Gao*, Xinyu Peng, Xin Deng, Changzhen Sun, Huayue Wu, Bin He*. Near infrared light responsive hybrid nanoparticles for synergistic therapy. Biomaterials, 2016, 100: 76-90.

8. Yan Liang, Xin Deng, Longgui Zhang, Xinyu Peng, Wenxia Gao, Jun Cao*, Zhongwei Gu, Bin He*. Terminal modification of polymeric micelles with π-conjugated moieties for efficient anticancer drug delivery. Biomaterials, 2015, 71: 1-10.

主要科研项目（近5年，不超过5项）

1.国家自然科学基金青年基金诱导肿瘤细胞自噬的胞内信号感知纳米药物分级释放系统 2019.01-2021.12 26万元

2.山东省自然科学基金兼具光动-化疗协同治疗和FRET示踪的多级pH敏感纳米载药系统 2018.03-2020.12 8万元

3.青岛市博士后应用项目兼具光动-化疗协同治疗和FRET示踪的多级pH敏感纳米载药系统 2018.01-2019.12 5万元

4.中国博士后面上基金可示踪的光动-化疗协同治疗的多级pH敏感纳米载药系统 2018.01-2019.12 5万元

5.海燕策略线路1book卓越人才科研启动费 5万元

电话:0532-82991508

邮箱:liangyan072@foxmail.com or liangyan@qdu.edu.cn