卢炜，副教授，硕士生导师

学习经历

2005.09-2009.07四川大学生命学院生物技术专业，本科

2009.09-2015.01中国科学院神经生物学专业，博士，导师：王晋辉

工作经历

2015.01-2017.09海燕策略线路1book，博士后

2017.09-2023.12海燕策略线路1book，讲师

2023.12-至今 海燕策略线路1book，副教授

个人简介：卢炜，海燕策略线路1book副教授。2009年本科毕业于四川大学，获学士学位。2015年于中国科学院大学获博士学位，2015年至2017年在海燕策略线路1book从事博士后研究。2017年入职海燕策略线路1book。目前的主要研究方向为离子通道在脑-肠轴及肠易激综合征中的靶标评估研究。在cerebral cortex, molecular brain, Biochemical Pharmacology等杂志累计发表sci研究论文20余篇，主持或参与国家及省基金6项。

目前主要研究方向：

1.内源性配体通过离子通道影响肠道动力机制

2.离子通道在肠易激综合征中的靶标评估

近期代表性成果

1.Sun C, Zhang L, Zhang M, Wang J, Rong S, Lu W, Dong H. Zinc pyrithione induces endothelium-dependent hyperpolarization-mediated mesenteric vasorelaxation in healthy and colitic mice. Biochem Pharmacol. 2023 Nov;217:115828. doi: 10.1016/j.bcp.2023.115828.

2.Lu Y, Yang J, Sun J, Lu W, Wang JH.mRNA and miRNA profiles in the nucleus accumbens are associated with psychological stress-induced susceptible and resilient mice. Pharmacol Biochem Behav. 2020 Dec;199:173062. doi: 10.1016/j.pbb.2020.173062.

3.Sun J, Lu Y, Yang J, Song Z, Lu W, Wang JH.mRNA and microRNA Profiles in the Amygdala Are Relevant to Susceptibility and Resilience to Psychological Stress Induced in Mice. J Mol Neurosci. 2020 Nov;70(11):1771-1796. doi: 10.1007/s12031-020-01570-3.

4.Yang J, Sun J, Lu Y, An T, Lu W, Wang JH.Revision to psychopharmacology mRNA and microRNA profiles are associated with stress susceptibility and resilience induced by psychological stress in the prefrontal cortex. Psychopharmacology (Berl). 2020 Oct;237(10):3067-3093. doi: 10.1007/s00213-020-05593-x.

5.Xu Z, Lu W, Miao Y, Li H, Xie X, Zhang F.mRNA profiling reveals the potential mechanism of TIPE2 in attenuating cognitive deficits in APP/PS1 mice. Int Immunopharmacol. 2020 Oct;87:106792. doi: 10.1016/j.intimp.2020.106792.

6.Du K, Lu W, Sun Y, Feng J, Wang JH.mRNA and miRNA profiles in the nucleus accumbens are related to fear memory and anxiety induced by physical or psychological stress. J Psychiatr Res. 2019 Nov;118:44-65. doi: 10.1016/j.jpsychires.2019.08.013.

7.Sun Y, Lu W, Du K, Wang JH.microRNA and mRNA profiles in the amygdala are relevant to fear memory induced by physical or psychological stress. J Neurophysiol. 2019 Sep 1;122(3):1002-1022. doi: 10.1152/jn.00215.2019

8.Feng J, Lu W, Wang D, Ma K, Song Z, Chen N, Sun Y, Du K, Shen M, Cui S, Wang JH.Barrel Cortical Neuron Integrates Triple Associated Signals for Their Memory Through Receiving Epigenetic-Mediated New Synapse Innervations. Cereb Cortex. 2017 Dec 1;27(12):5858-5871. doi: 10.1093/cercor/bhx292.

9.Lu W, Wen B, Zhang F, Wang JH.Voltage-independent sodium channels emerge for an expression of activity-induced spontaneous spikes in GABAergic neurons. Mol Brain. 2014 May 20;7:38. doi: 10.1186/1756-6606-7-38

邮箱:luwei@qdu.edu.cn