姓名：郭瑞红

学历职称：博士研究生，青年卓越人才，讲师

教育与工作经历：

2017.03-2020.02，韩国全南大学，博士

2021.11-2024.01，中国海洋大学，博士后

2024.01-至今，海燕策略线路1book药理系，讲师

研究领域方向：

1.离子通道作为消化道肿瘤及炎症的靶标确认及机制研究

2.靶向离子通道抗肿瘤及抗炎症药物的筛选

代表性研究成果：

科研项目：

1.国家自然科学青年基金（在研，主持）

2.山东省自然科学青年基金（在研，主持）

3.山东省博士后创新项目（在研，主持）

4.中国博士后科学基金面上项目（已结题）

5.青岛市博士后应用资助项目（已结题）

代表性论文:

1.Guo RH, Im YJ, Shin SI, Jeong K, Rhee JH, Kim YR. 2019.Vibrio vulnificusRtxA1 cytotoxin targets filamin A to regulate PAK1- and MAPK-dependent cytoskeleton reorganization and cell death.Emerg Microbes Infect.8(1):934-945.

2.Guo RH, Lim JY, Tra My DN, Jo SJ, Park JU, Rhee JH, Kim YR. 2018.VibriovulnificusRtxA1 toxin expression upon contact with host cells is RpoS-dependent.Front Cell Infect Microbiol.8:70.

3.Guo RH, Park JU, Jo SJ, Ahn JH, Park JH, Yang JY, Lee SS, Park MJ, Kim YR. 2018. Anti-allergic inflammatory effects of the essential oil from fruits ofZanthoxylum coreanumNakai.Front Pharmacol.9:1441.

4.Guo RH, Gong Y, Kim SY, Rhee JH, Kim YR. 2020. DIDS inhibitsVibrio vulnificuscytotoxicity by interfering with TolC-mediated RtxA1 toxin secretion.Eur J Pharmacol.884:173407.

5.Guo RH, Kim SJ, Choi CH, Na CS, Kang BY, Kim YR. 2019. Inhibitory effects of ChondroT and its constituent herbs on RANKL-induced osteoclastogenesis.BMC ComplementMed Ther.19(1):319.

6. Su XD^#,Guo RH^#, Li HX, Ma JY, Kim YR, Kim YH, Yang SY. 2018. Anti-allergic inflammatory components fromSanguisorba officinalisL.Bioorg Med Chem Lett. 28(12):2210-2216.

7.Guo RH, Yuan YL, Liu RH, Hong W, Zhou Y, Zhao WB, Wang XL and Zhang XH. 2023.Vibrio paucivoranssp. nov. andVibrio qingdaonensissp. nov., two marine bacteria isolated from the marginal seas of China.IJSEM. 73:005822.

8.Su XD^#,Guo RH^#, Yang SY, Kim YH, Kim YR. 2019. Anti-bacterial effects of components fromSanguisorba officinalisL. onVibrio vulnificusand their soluble epoxide hydrolase inhibitory.Nat Prod Res. 33(23):3445-3449.

9.Gong Y,Guo RH, Rhee JH, Kim YR. 2021. TolV1 has multifaceted roles duringVibrio vulnificusinfection.Front Cell Infect Microbiol. 11:1-8.

联系方式

邮箱：guoruihong@qdu.edu.cn;guorhyx@163.com